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In parallel, genetic predisposition (such as mutations in the FOXO3A gene) lead to the inefficiency of antioxidant mechanisms, observed by an increase in the superoxide dismutase (SOD) enzyme, reduction in catalase (CAT) and glutathione (Glu), causing an imbalance in the redox status

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The fact that KA injection into the amygdala showed similar effects to hippocampal delivery further suggests the role of the amygdala in epilepsy, as well as a potential mechanism for anxiety that accompanies epilepsy